Regie: Norton Virgien
Die amerikanischen Kult-Babies erleben jede Menge Abenteuer. Tommy und seine Freunde machen sich auf den Weg, um den neugeborenen Bruder zurück ins Krankenhaus zu bringen. Unterwegs treffen die kleinen Knirpse auf viele Hindernisse und zu allem Übel heftet sich auch noch die schreckliche Cousine Angelica an ihre Fersen.
Whoopi Goldberg
Ranger Margaret (voice)
David Spade
Ranger Frank (voice)
E. G. Daily
Tommy Pickles (voice)
Tara Strong
Dilan "Dil" Pickles (voice)
Christine Cavanaugh
Chuckie Finster (voice)
Kath Soucie
Phil / Lil / Betty DeVille (voices)
Cheryl Chase
Angelica Pickles (voice)
Tim Curry
Rex Pester (voice)
Jack Riley
Stuart 'Stu' Pickles (voice)
Busta Rhymes
Reptar Wagon (voice)
Michael Bell
Charles 'Chaz' Finster Sr. / Grandpa Boris Kropotkin / Drew Pickles (voice)
Joe Alaskey
Grandpa Lou Pickles (voice)
Phil Proctor
Howard DeVille / Igor (voice)
Cree Summer
Susie Carmichael (voice)
Tress MacNeille
Charlotte Pickles (voice)
Melanie Chartoff
Didi Pickles / Minka Kropotkin (voice)
Hattie Winston
Lucy Carmichael (voice)
Andrea Martin
Aunt Miriam (voice)
Tony Jay
Dr. Lipschitz (voice)
Abraham Benrubi
Serge (voice)
Whoopi Goldberg
Ranger Margaret (voice)
David Spade
Ranger Frank (voice)
E. G. Daily
Tommy Pickles (voice)
Tara Strong
Dilan "Dil" Pickles (voice)
Christine Cavanaugh
Chuckie Finster (voice)
Kath Soucie
Phil / Lil / Betty DeVille (voices)
Cheryl Chase
Angelica Pickles (voice)
Tim Curry
Rex Pester (voice)
Jack Riley
Stuart 'Stu' Pickles (voice)
Busta Rhymes
Reptar Wagon (voice)
Michael Bell
Charles 'Chaz' Finster Sr. / Grandpa Boris Kropotkin / Drew Pickles (voice)
Joe Alaskey
Grandpa Lou Pickles (voice)
Phil Proctor
Howard DeVille / Igor (voice)
Cree Summer
Susie Carmichael (voice)
Tress MacNeille
Charlotte Pickles (voice)
Melanie Chartoff
Didi Pickles / Minka Kropotkin (voice)
Hattie Winston
Lucy Carmichael (voice)
Andrea Martin
Aunt Miriam (voice)
Tony Jay
Dr. Lipschitz (voice)
Abraham Benrubi
Serge (voice)
Whoopi Goldberg
Ranger Margaret (voice)
David Spade
Ranger Frank (voice)
E. G. Daily
Tommy Pickles (voice)
Tara Strong
Dilan "Dil" Pickles (voice)
Christine Cavanaugh
Chuckie Finster (voice)
Kath Soucie
Phil / Lil / Betty DeVille (voices)
Cheryl Chase
Angelica Pickles (voice)
Tim Curry
Rex Pester (voice)
Jack Riley
Stuart 'Stu' Pickles (voice)
Busta Rhymes
Reptar Wagon (voice)
Michael Bell
Charles 'Chaz' Finster Sr. / Grandpa Boris Kropotkin / Drew Pickles (voice)
Joe Alaskey
Grandpa Lou Pickles (voice)
Phil Proctor
Howard DeVille / Igor (voice)
Cree Summer
Susie Carmichael (voice)
Tress MacNeille
Charlotte Pickles (voice)
Melanie Chartoff
Didi Pickles / Minka Kropotkin (voice)
Hattie Winston
Lucy Carmichael (voice)
Andrea Martin
Aunt Miriam (voice)
Tony Jay
Dr. Lipschitz (voice)
Abraham Benrubi
Serge (voice)